MRI Scans Could Leave Toxic Traces in Your Body, Scientists Warn!

A contrast MRI is a type of magnetic resonance imaging (MRI) scan that uses a special dye to improve the visibility of tissues, organs, and blood vessels. This contrast agent —often containing gadolinium—is injected into the bloodstream, making certain areas stand out more clearly in the images.

Scientists have discovered a potential link between MRI contrast dye and toxic material buildup in the body. Researchers at the University of New Mexico (UNM) found that oxalic acid, a molecule present in foods like spinach, chocolate, and almonds, may interact with gadolinium, the heavy metal used in MRI contrast agents. This interaction could lead to the formation of harmful nanoparticles that infiltrate organs.

In a new paper published in the journal Magnetic Resonance Imaging, a team led by Brent Wagner, MD, professor in the Department of Internal Medicine in the UNM School of Medicine, sought to explain the formation of the nanoparticles, which have been associated with serious health problems in the kidneys and other organs.

While most patients experience no adverse effects, some have reported reactions ranging from mild swelling and headaches to more severe conditions like nephrogenic systemic fibrosis, which can cause skin thickening and organ damage. The findings suggest that individuals undergoing MRI scans with contrast might want to avoid Vitamin C supplements, as they can increase oxalic acid levels.

This discovery could lead to new safety recommendations for MRI procedures.

How Gadolinium is used in MRI scans?

Gadolinium-based contrast agents (GBCAs) are used in MRI scans to enhance the visibility of soft tissues. Gadolinium is a heavy metal with unique magnetic properties, making it ideal for MRI imaging. However, because raw gadolinium is toxic, it’s chemically bonded to molecules (called chelators) to make it safe for medical use.

How it Works:

1. Injection – The contrast agent is injected into the bloodstream, usually through an IV.
2. Magnetic Interaction – Gadolinium influences the magnetic fields used in MRI, causing tissues with high blood flow (like tumors or inflamed areas) to appear brighter.
3. Better Imaging – This enhancement helps doctors differentiate between normal and abnormal tissues, making it easier to detect brain disorders, cancer, and vascular diseases.

Despite its benefits, there has been concern over gadolinium retention in the body, especially in patients with kidney issues. Research continues into safer alternatives and better ways to remove any lingering traces.

“The worst disease caused by MRI contrast agents is nephrogenic systemic fibrosis,” said Professor Brent Wagner. “People have succumbed after just a single dose.” The condition can cause a thickening and hardening of the skin, heart and lungs and cause painful contracture of the joints."

The medical community has mixed reactions to MRI contrast agents, particularly those containing gadolinium. While they are widely used to enhance imaging, concerns have grown over potential side effects and long-term retention in the body.

Scientists are exploring safer alternatives and ways to minimize gadolinium retention in the body.